It will depend on how much timing is pulled currently due to detonation. If none, then I would expect to see no gains. It takes quite a bit of octane booster to actually get your octane points up. The classic method used by the boost guys was to add toluene which is quite cheap in comparison to the 16oz octane booster. Note octane boosters usually add (max) to the increase in octane...considering a 10gal tank. With a bottle of octane booster, you will probably barely get over 1 point of increase in a 18gal tank.
Furthermore there is discussions that because this is homebrew, it will lead to more deposits than a detergent fuel from a refinery. Unless you are seeing detonation, I do not see the point. Bad gas in your area?
Octane boosters have minimal gains. Don't fall into the marketing hype. As Fig mentioned, octane boosters only boost your octane by 1 point, not whole octane figures. Keep that engine tuned and have the engine flushed if you have heavy carbon buildup.